Archive

Monthly Archives: April 2014

With Elizabeth’s care shrouded in secrecy since leaving the Bethlem and then being transferred to Cambian under Section 3 it has been hard to see what is going on under those circumstances but the truth always comes out in the end.  When you are only allowed 1 day and 1 night to share amongst the family and most of that time was spent travelling from Wales.  Never before have we as a family been allowed to have Elizabeth for a week like at Easter but that is when you see what is being dished out.

As you know I got 500mg a day taken off (Metformin) as the GP could see no reason why this was ever prescribed.  It was prescribed alongside Clozapine which is contra indicated.   I felt so happy as the least drugs the better as far as I am concerned as I know what damage this is all doing to Elizabeth.  However when I looked at the drugs chart given with the medication brought home there were others mentioned ie Bisoprolol which is a Beta Blocker used to treat hypertension.  I can only assume Elizabeth has high blood pressure or heart problems now associated with taking Clozapine.    Anyway I looked up this additional drug which was not included with the drugs sent home for her to take  –  “stopping suddenly may make your condition worse or cause other serious heart problems”  “Bisoprolol can cause side effects that may impair your thinking or reactions.”   

Tell your healthcare provider:

If you have asthma, bronchitis, emphysema

With diabetes – “Bisoprolol makes it harder for you to tell when you have low blood sugar

Thyroid Disorder/liver/kidney disease.

Also Raynaud’s syndrome which I am concerned about because Elizabeth was ice cold with her hands on a hot sunnyday.

 

It gives a list of other drugs that can affect Bisoprolol etc. – even vitamins

I am most concerned about this other list of drugs that the team are giving to Elizabeth which also includes Senna as of course Clozapine is a drug that can cause constipation and just take a look at Northampton Hospital as an example there where professionals do not give proper case leading to death.

I have also seen Lorazepam and Paracetamol prescribed so every time Elizabeth mentions she feels stressed or has a headache the staff dish out more and more drugs.

Anyway I have sought advice and Clozapine is contra indicated in heart disease for a start and Senna is often concomitantly prescribed with high doses of Clozapine (Page 222 BNF 60) and 350 mg is high.  Also I have been told it is strange that PRN Lorazepam is being used with such a high dose.  If 350mg is not controlling the agitation then it would make more sense to titrate Clozapine down and it has been suggested about titrating up with Risperidone which is another 5-HT antagonist.   I can see that the Clozapine is not doing Elizabeth any good at all.

 

I am appalled that I am having to ask about the whereabouts of the supplements which have disappeared into thin air alongside the oils from Dr Tracy.  The truth always comes out in the end and I will check thoroughly when I am next down as I am waiting for a response in writing – whilst £200 is not a huge amount of money I would like to know where these are – it is the principal.  This is why I am not happy at being requested by Elizabeth to provide more fish oil when these things have disappeared that I originally provided.  The GP should provide them instead of all the poisonous drugs she is on now.   I have been advised not to use some supplements which are interactive and toxic and that I should check the formularly and never to use St John’s Wort or any other herbal treatments as they are as dangerous as the pharma manufactured treatments.   Well I need to watch that the team do not plrescribe any other anti-pscyhotics as this drug Bisoprolol should be used with caution where other anti-psychotics are prescribed.  Just about all the D2 (Dopamine) antagonist drugs are associated with cardiac ventricular arrhythmias

Anyway I am not happy that all these drugs are given to my daughter and they are causing her to have side effects.

Because of my concerns the team are calling a meeting and I wonder if the family will be included as this has not been the case in the past.

The new Consultant Psychiatrist has failed to ring me despite my requests and I have made it clear I am far from happy.  It is not the care home or the staff or activities it is the treatment.  What kind of treatment is this when someone is treatment resistant and can remember everything for a start but worse of all is the treatment called ECT where people lose happy memories and this is forced upon patients under Section.   It is barbaric what is going on in the UK.

 

I am in favour of the research in metabolism as if is proven that someone cannot metabolise the drugs and they are doing more harm than good the this will lead the way for someone to be reduced off these drugs and unlike at present decent facilities provided for when things go wrong as in the case of Elizabeth as NONE of these mind altering drugs have worked.   For Elizabeth’s condition of PTSD (or underlying endocrinal disorder the drugs are ineffective and a waste of taxpayer’s money.  As you can see there is no end of drugs available for Elizabeth to take yet someone may need a life-saving drug for a physical condition and are denied this –  why not stop pushing the drugs at my daughter and then there will be more money available for those who genuinely need these life saving drugs – better as none of these drugs have worked for Elizabeth and the NHS would save a fortune by not pushing drug are drug at psychiatric patients when all along they could have a physical problem instead.  No wonder they do not get better and they could be doing more harm than good.   For example Clozapine given to refractive patients is a weak dopamine receptor antagonist meaning the symptoms cannot be linked to excessive dopamine in the brain.    Clozapine inhibits 5-HT serotonin, muscarinic, histamine and alpha-adreno-receptors.  I have received some very good advice about this which I have posted already. 

I am waiting to hear about this meeting right now.   I would be prepared to take Elizabeth abroad to get decent care and have proper assessments – this is where the money should be spent so that people like Elizabeth can get the correct treatment, not just a catalogue of psychiatric drugs. 

 

 

 

 

      

 

 

 

 

 

 

Advertisements

1-17-07VeraSharavTestimonyUNITED STATES DISTRICT COURT
EASTERN DISTRICT OF NEW YORK
2 ——————————x
IN RE:
3 ZYPREXA LITIGATION,
4 MDL 04 1596
5 United States Courthouse
Brooklyn, New York
6 ——————————x
7 January 17, 2007
11:00 a.m.
8
TRANSCRIPT OF HEARING
9 Before: HON. JACK B. WEINSTEIN, District Judge
10 APPEARANCES
11 Attorneys for Plaintiff:
12 DOUGLAS & LONDON, ESQ.
111 John Street
13 Suite 1400
New York, N.Y. 10038
14 BY: MICHAEL A. LONDON, ESQ.
15
THE MILLER FIRM
16 The Sherman Building
108 Railroad Avenue
17 Orange, Virginia 22960
BY: MICHAEL J. MILLER, ESQ.
18
19
20 FRED VON LOHMANN, ESQ.
Attorney for Electronic Frontier Foundation
21 454 Shotwell Street
San Francisco, Ca 94110
22
23
24
25
67
1 Attorneys for Defendant:
2 PEPPER HAMILTON
Attorney for Eli Lilly
3 3000 Two Logan Square
Eighteenth and Arch Streets
4 Philadelphia, Pa 19103-2799
BY: SEAN P. FAHEY, ESQ.
5 GEORGE A. LEHNER, ESQ.
NINA M. GUSSACK, ESQ.
6 ANDREW R. ROGOFF, ESQ.
7
8
9 McCARTER ENGLISH
Attorneys for Eli Lilly & Company
10 245 Park Avenue
New York, N.Y. 10167
11 BY: SAMUEL J. ABATE, JR., ESQ.
12
13 SHERMAN, SILVERSTEIN, KOHL, ROSE & PODOLSKY
Attorneys for Vera Sharav, David Cohen, AHRP
14 4300 Haddonfield Road
Suite 311
15 Pennsauken, New Jersey 08109
BY: ALAN C. MILSTEIN, ESQ.
16
17
KOOB & MAGOOLAGHAN
18 Attorneys for Dr. Eagleman
South Street Seaport
19 19 Fulton Street
New York, N.Y. 10038
20 BY: ALEXANDER A. REINERT, ESQ.
21
22
23
24
25
68
1 APPEARANCES: (Continued)
2
3 EDWARD HAYES, ESQ.
Attorney for Mr. Gottstein
4
5 JOHN McKAY, ESQ.
Attorney for Mr. Gottstein
6
7
8 Allan R. Sherman, CSR, RPR
225 Cadman Plaza East
9 Brooklyn, New York 11201
Tel: (718) 260-2529 Fax: (718) 254-7237
10
11 Proceedings recorded by mechanical stenography, transcript
produced by computer.
12
13
14
15
16
17
18
19
20
21
22
23
24
25
161
1 MR. HAYES: Right.
2 THE COURT: I think it’s reasonable to read the
3 letter plus the attachment as indicating December 20th as the
4 date for supplying the exhibits.
5 MR. McKAY: Your Honor —
6 THE COURT: Do you want to ask anything?
7 MR. McKAY: No, your Honor. I think that it’s
8 really argumentative. It’s the date of the deposition and we
9 agree with that.
10 THE COURT: Then I’m prepared to release the
11 witness.
12 MR. HAYES: Yes.
13 THE COURT: Have a good trip back to Alaska, sir?
14 THE WITNESS: Thank you, your Honor.
15 (Witness excused.)
16 THE COURT: Next witness.
17 MR. LEHNER: At this time we would call Vera Sharav
18 who is still in the courtroom, I believe.
19 VERA SHARAV, having been called as a
20 witness, first being duly sworn, was examined and
21 testified as follows:
22 THE CLERK: Could you please spell your name for the
23 court reporter.
24 THE WITNESS: Vera Sharav, V-E-R-A S-H-A-R-A-V.
25 DIRECT EXAMINATION
162
1 BY MR. LEHNER:
2 Q Good afternoon, Mr. Sharav.
3 My name is George Lehner and I represent Lilly in
4 this proceeding.
5 Can you tell us when you first met Mr. Gottstein,
6 under what circumstances?
7 A That’s hard to tell because I don’t really remember.
8 Face-to-face when did I meet him?
9 Q When did you first become acquainted with him?
10 A I became acquainted with his work with Psych Rights Law
11 Project.
12 Q When was that?
13 A That might have been two years ago. I don’t have an
14 exact.
15 Q 20?
16 A 2 years ago perhaps.
17 Q And over the last two years, what kind of contact have
18 you had with Mr. Gottstein?
19 A All kinds of contact. We have similar goals in certain
20 ways and we sometimes collaborate and I spoke, gave a
21 presentation at a conference that he held on November 17th for
22 the National Association For Rights Advocacy. I forgot the
23 last name but it’s NAPA. It’s an organization for psychiatric
24 patients’ rights.
25 Q So it’s fair to say over the last two years you’ve had
163
1 regular contact with Mr. Gottstein, is that correct?
2 A As I do with very many advocates.
3 Q And the conference that you mentioned on November 17,
4 that was, you were with Mr. Gottstein at that particular
5 conference?
6 A He organized it. I was invited as a speaker and went to
7 Baltimore and presented to them, yes.
8 Q At that conference did you and Mr. Gottstein have an
9 occasion to talk about Zyprexa and the litigation that was
10 ongoing at the time?
11 A No.
12 Q And if you let me finish my question, it will make it a
13 lot easier for the court reporter and I’ll try not to
14 interrupt your answer as well.
15 My question was, and I think if I understood, your
16 answer was that you did not have any occasion to discuss
17 Zyprexa with Mr. Gottstein when you were with him on
18 November 17?
19 A I was actually together with my husband so I didn’t have
20 these private conversations. It was a conference as I said.
21 Q Let me ask you, and you’ve been in the courtroom and
22 you’ve heard testimony about the documents that Mr. Gottstein
23 received from Dr. Egilman.
24 When did you first receive a copy of the documents
25 that we’ve been talking about here today, those documents that
164
1 Dr. Egilman produced to Mr. Gottstein?
2 A I believe it was on the 18th. I have the document with
3 me. The stamp was the 14th. In other words, it left Alaska
4 on the 14th. I didn’t get it before the 18th. It was a
5 weekend.
6 Q They were mailed to you?
7 A Yes.
8 Q You said you had the documents with you?
9 A Yes.
10 Q Is that a DVD version?
11 A Yes.
12 Q It’s the only copy you were provided?
13 A What I have is what I was provided.
14 Q Had you been alerted that these documents were going to
15 be sent to you before the time they actually arrived when they
16 arrived at your home?
17 A I had received word that the documents had been posted
18 and I was given the website and I tried to open it and I
19 couldn’t. So I sent Jim an E-mail and said I can’t open it.
20 Q Let take that apart a little bit.
21 You had received word. Who had you received word
22 from?
23 A I believe it was — I think it was Bob Whitiker. I’m not
24 sure but this was — you have to understand that when those
25 documents evidently went up, I was in Washington at an FDA
165
1 hearing where I had to conduct a press briefing about
2 antidepressants and suicidality so I was quite out of it and
3 came back on 14th at which time I had a barrage of E-mails
4 from different people about the Zyprexa documents being up on
5 the web.
6 Q So you came back from a conference in Washington or a
7 meeting in Washington?
8 A A hearing, an FDA advisory hearing.
9 Q On the 14th?
10 A Yes. I was there the 12th and 13th.
11 Q Which was a Thursday?
12 A I guess.
13 Q At that point you had a barrage of E-mails alerting you
14 that the documents that had been provided by Dr. Egilman to
15 Mr. Gottstein were on a website?
16 A That’s not exactly how it was put, but what was said was
17 that the Zyprexa documents were up on the website, yes.
18 Q And do you recall from whom you received —
19 A As I said, there were many. There is a network, people,
20 and you get actually lots of duplicates.
21 Q I’m going to ask you again, please don’t interrupt me and
22 I won’t interrupt you.
23 My question was: Do you recall some of the people
24 who sent you that E-mail? I understand it was a barrage but
25 from whom did you receive the E-mail?
166
1 A Actually from far and wide. There are advocate in the
2 U.K., Australia, Canada. Word travels on the internet and
3 that is in fact the big connecting factor for people who don’t
4 have great many resources and who don’t have many lawyers.
5 The internet is the way that there is a constant interchange
6 and that is how it happens.
7 Q Do you still have your computer on which you received the
8 barrage of E-mails?
9 A Probably some have probably been deleted but some I still
10 have.
11 Q Do you still maintain the same computer on which they
12 were received?
13 A Yes.
14 Q Did you have any conversations with anybody after you
15 received these E-mails and before you actually received the
16 physical package containing the disc containing the documents?
17 A No, I just —
18 Q Did you have any conversation with anybody about what
19 these documents may be that were in the mail on their way to
20 you between the 14th and the time they arrived at your home?
21 A I think you have to understand that many of us were quite
22 aware that the documents had first been obtained in what is
23 now referred to as the Zyprexa 1 trial, the one in which there
24 were 8,000 plaintiffs and Lilly paid some $690 million which
25 we regard as money to keep the documents out of the public
167
1 domain.
2 And so there was guessing as to what was in them.
3 We also know from documents from the FDA and from pre-clinical
4 — before the drug was approved as to some of the problems and
5 the fact that diabetes is now an epidemic —
6 Q What I want to really focus on are the conversations that
7 you had about how you learned what was in these documents.
8 You said you became aware even before the time the documents
9 were on their way to you what was in those documents.
10 How did you become aware of that?
11 A As I just explained, the adverse events that have been
12 observed in clinical practice —
13 Q So —
14 A I would also like not to be interrupted.
15 Q The first time I did it and I apologize.
16 A The fact that patients are getting diabetes,
17 cardiovascular dysfunction, hyperglycemia, that people are
18 dying, this is what is really the issue here. People are
19 dying from this drug. So getting documents that validate the
20 clinical evidence is very important to us.
21 Q Let me focus a little bit more on what you did when you
22 actually received the documents than on the weekend after you
23 got back.
24 The 18th was on a Monday?
25 A It could not have been before Monday and I get mail in
168
1 the afternoon.
2 Q The documents arrived in the mail, what did you do at
3 that point with this disc? It’s a computer disc?
4 A I had it. I didn’t do anything with it but I got some
5 calls.
6 Q Did you load it up on your own computer?
7 A Yes.
8 Q And you tried to open it?
9 A Yes.
10 Q And were you able to open it?
11 A Yes, I was.
12 Q Did you print up any of those documents?
13 A Yes.
14 Q And did you then distribute the documents that you
15 printed to anybody or give them to anybody?
16 A I read the documents or some of them.
17 Q Did you give them to anybody else?
18 A I had calls from a couple of press people and two came,
19 borrowed the disks, made copies and returned them. I didn’t
20 do it.
21 Q Who were these people?
22 A Wall Street Journal, Bloomberg News.
23 Q That was done on the afternoon of the 19th or the 18th?
24 A The 18th I think — 18th and 19th, morning.
25 Q Were you aware when you received these documents that
169
1 they had been the subject of what has been described here and
2 you’ve heard the testimony of a protective order that had been
3 entered into this case?
4 A I don’t know about a protective order about the case.
5 What I was given to understand is that the documents were
6 obtained legally, that certain legal procedures were
7 undertaken and that’s it and I accepted that. And of course
8 by the time I got them, they had been in the New York Times so
9 I figured that is the public domain.
10 Q Who had given you the understanding that they had been
11 obtained legally? Who told you that they had been obtained
12 legally? You said you had been given an understanding?
13 A That would be Jim Gottstein.
14 Q So you spoke to Jim Gottstein over the weekend?
15 A I spoke to him when I couldn’t open the link. Remember.
16 I couldn’t, in other words, download it myself so I said can
17 you send me it.
18 Q So you called Mr. Gottstein, said I’m trying to download
19 these documents from a link I have, I’m not able for open them
20 and you had a conversation with Mr. Gottstein at that time?
21 A Yes.
22 Q During that conversation you were led to believe that
23 these documents had been obtained legally?
24 A Yes.
25 Q And that understanding was provided to you by Mr.
170
1 Gottstein, is that correct?
2 A It was validated in my mind when they appeared on Sunday
3 in the New York Times front page, then again on Monday on the
4 front page. Then of course the editorial calling for
5 congressional hearings about the content of the documents and
6 that is really my interest. My interest is the content
7 because the documents document the fact that Eli Lilly knew
8 that the — that Zyprexa causes diabetes. They knew it from a
9 group of doctors that they hired who told them you have to
10 come clean. That was in 2000. And instead of warning doctors
11 who are widely prescribing the drug, Eli Lilly set about in an
12 aggressive marketing campaign to primary doctors. Little
13 children are being given this drug. Little children are being
14 exposed to horrific diseases that end their lives shorter.
15 Now, I consider that a major crime and to continue
16 to conceal these facts from the public is I think really not
17 in the public interest. This is a safety issue.
18 MR. LEHNER: I move to strike as being nonresponsive
19 to my last question and I would like to ask the court reporter
20 if he is able to — I think I remember my last question. I’ll
21 repeat my last question. Nonetheless, I’ll make a motion to
22 strike the last answer.
23 THE COURT: Denied.
24 Q My question was was it Mr. Gottstein who conveyed to you
25 the impression that you formed in your mind that these
171
1 documents had been obtained legally?
2 A Yes.
3 Q So the answer to that is yes?
4 A Yes.
5 Q Thank you very much.
6 Now, when he conveyed to you that the documents had
7 been obtained legally, did he tell you that they had been in
8 his view subject to a protective order at one point in time?
9 A By this time I don’t know any more about protective. The
10 next thing that came were an E-mail like I think from one of
11 your lawyers.
12 Q So at some point you learned that these documents were
13 subject to a protective order and were in fact considered by
14 Eli Lilly to be confidential documents, is that correct?
15 A I realized that there was contention around it. I did
16 not accept necessarily what Eli Lilly’s interpretation is.
17 Q I’m not asking you that.
18 You understood that there was at least a belief by
19 Eli Lilly and perhaps others that these documents were still
20 subject to the protection of the Court under the protective
21 order?
22 A No, I don’t really — I have to admit, protective order
23 pro se does not mean the same thing to me as it does to you.
24 Q You understand that they were designed to be kept
25 confidential?
172
1 A Except that they were open in the New York Times. That
2 signalled that they were open to the public.
3 Q Were there any documents that were actually reprinted in
4 the New York Times or was it actually a story?
5 A There were quotes from documents.
6 Q No whole pages or whole documents in the New York Times?
7 A No, but there were quotes from extensive documents.
8 Q Did you ever consult or consider consulting a lawyer to
9 determine the fact of whether you received this does put you
10 in any type of legal jeopardy?
11 MR. MILSTEIN: That would be attorney/client
12 privilege.
13 MR. LEHNER: I’m not asking whether she consulted a
14 lawyer.
15 THE COURT: Address your remarks to me. She is just
16 being asked about whether she consulted. That is not
17 privilege.
18 A I did not think I had any reason to.
19 Q Did you ever consider whether or not there was any
20 opportunity to contact Eli Lilly or to contact Mr. Gottstein
21 or any of the attorneys that you had become aware were
22 involved in this controversy and determine whether or not
23 there was a procedure that had been set up to determine
24 whether or not these documents should be kept confidential?
25 A I’m afraid that after they appeared in the New York
173
1 Times, I did not think that it was my obligation to go hunting
2 for what Eli Lilly considered or didn’t consider. That really
3 is not my purview.
4 Q Now, I’ll ask that this be marked as Petitioner’s
5 number 7, please — 8.
6 THE COURT: You are offering it in evidence?
7 MR. LEHNER: I am, your Honor.
8 THE COURT: Admitted.
9 (So marked in evidence Petitioner’s Exhibit 8.)
10 Q Have you had an opportunity to review what has been
11 marked as Petitioner’s 8?
12 A Yes.
13 Q And if I’m correct, this is an E-mail that was sent from
14 Mr. Jim Gottstein to Veracare. Is that your E-mail address?
15 A Yes.
16 Q And it was sent on Tuesday December 19th?
17 A Yes.
18 Q And it’s copied to Mr. Gottstein and Mr. McKay and Mr.
19 Woodin, somebody at the Lanier law firm, an address
20 emj@lanierlawfirm, an address rdm at the Lanier law firm,
21 gentleman at the law firm of Elaine Powell?
22 A These weren’t familiar to me, of course.
23 Q The only name that is familiar on there I take it is Mr.
24 Gottstein?
25 A Yes.
174
1 Q He sent you this E-mail on December 19 and if you would
2 read the first two lines of the E-mail.
3 A “I mailed you two DVDs with some documents on them
4 pertaining to Zyprexa and have been orally ordered to have
5 them returned too.”
6 Q Now you indicated earlier on that you received one DVD.
7 Did you receive one or in fact receive two?
8 A 2.
9 Q So you received two DVDs?
10 A Yes.
11 Q Have you brought both of these DVDs with you here today?
12 A Yes.
13 Q You brought both of them here with you today?
14 A Yes.
15 Q My questions earlier on about opening the documents
16 loading them on your computer, my understanding was we were
17 talking about one DVD but did you in fact open up both DVDs
18 and copy both DVDs onto your computer?
19 A I did one. I assumed they were duplicates.
20 Q Did you look at the second DVD to determine if it was a
21 duplicate?
22 A No, I didn’t have time. This is very laborious.
23 Q Was there something in the package to indicate to you
24 that these were duplicates of one DVD?
25 Was there anything in the packet itself that
175
1 suggested that these were duplicates of the same DVD?
2 A No, I had asked for two copies.
3 Q Who did you ask for two copies?
4 A From Jim.
5 Q So you had a communication with Jim?
6 A That was the same communication that I referred to
7 earlier. When I couldn’t open it and download it myself, I
8 indicated that to him.
9 Q And what was your interest in having two copies?
10 A I wanted to take one to the New York State Attorney
11 General.
12 Q Now, this E-mail goes on and gives the address to whom
13 Mr. Gottstein has been asked to send these DVDs back. And it
14 gives a link to the proposed order in the case.
15 Did you open up that link and read the order?
16 A No, I didn’t, actually because I noticed that he said he
17 was orally ordered and I didn’t think that orally ordered was
18 a Court order and I wanted to hear that there would be a
19 hearing or some sort of thing in court and then I would of
20 course follow that. But when it says I’ve been orally
21 ordered, that sounded peculiar to me. It didn’t sound like an
22 order from the Court.
23 MR. CHABASINSKI: Your Honor, I cannot hear the
24 witness at all.
25 THE WITNESS: Can you hear now?
176
1 MR. CHABASINSKI: Yes, thank you.
2 Q Would you go on and read the rest of the E-mail after the
3 address. The address — we’ll stipulate the document says to
4 Mr. Peter Woodin. Then it gives a website, but if you would
5 read that paragraph that begins starting with a copy.
6 A “A copy of the proposed written order is posted at Psych
7 Rights — that is the organization and so forth — with a
8 comment about certain language which I strenuously disagree
9 with and we are trying to get eliminated from the signed
10 order.
11 Q Would you read the next paragraph?
12 A “Regardless, please return the DVD, hard copies and other
13 copies to Special Master Woodin immediately. If you have not
14 yet received it, please return it to Special Master Woodin
15 when you do receive it. In addition, please insure that no
16 copies exist on your computer or any other computer equipment
17 or in any other format, websites or FTP sites or otherwise on
18 the internet. There is a question in my mind that the Court
19 actually has jurisdiction over me to issue the order. I
20 believe I came into the documents completely legally but the
21 consequences to me if I am wrong about the jurisdiction issue
22 are severe so I would very much appreciate your compliance
23 with this request.”
24 Q I take it that you did not return the DVD to Mr.
25 Gottstein or to Special Master Woodin, is that correct?
177
1 A That’s correct.
2 Q And you did not return the hard copies or any copies of
3 the hard copies that you made to Special Master Woodin, is
4 that correct?
5 A That’s correct.
6 Q And I take it that you did not check your computer to
7 make sure that no copies of the documents once you had opened
8 them on your computer existed, is that correct?
9 A That’s correct.
10 Q Why not?
11 A In the meantime, I also had word that there would be a
12 hearing.
13 Q When did you first get word that there would be a
14 hearing?
15 A I don’t know the exact date but this was very much in
16 tandem because the first thing I heard, I think the first
17 communication was from your cocounsel —
18 What’s his name?
19 It’s not listed here. Fahey.
20 So that there were cross-signals going on and I did
21 see that there would be a Court hearing and I decided to wait
22 for that.
23 Q Was there anything in the notice that you received about
24 the court hearing that suggested that the order that had been
25 given here to return these documents was somehow being
178
1 withdrawn?
2 A As I say, this is coming to me not from the Court, it’s
3 coming from James saying that he was ordered orally and
4 telling it to me. That is not direct instruction from the
5 Court.
6 Q But the same time as you testified, you didn’t feel it
7 was necessary to even push on the link here where you could
8 read the order yourself, that was your testimony?
9 A It’s —
10 Q That was your testimony, isn’t that correct?
11 A Jim posted many documents during this time. I did not go
12 to each one because I was busy also with other things. The
13 Zyprexa thing, as important as it is, was not the only thing
14 that I had to deal with during this period.
15 So no, I did not go and download each of the
16 documents. They were coming fast and furious.
17 Q Let’s go back and look at the website address to see
18 whether that might have heightened your concern about what
19 this particular document was.
20 That website address reads
21 http://PsychRights.org/states/Alaska/caseXX/Eli Lilly/proposed
22 order.
23 Is that correct?
24 A Proposed order.
25 Q And you read that?
179
1 A Proposed order. It’s not a definite thing. I did not
2 take that as a definite. It says proposed order.
3 Q So you reread that in this E-mail and decided I don’t
4 need to open this?
5 A That’s right.
6 Q Do you recall receiving the order dated December 29 from
7 this Court which was I think transmitted to you by Mr. Fahey
8 among others?
9 A I do and I took that one seriously.
10 Q Did you return the documents as a result of receiving
11 that particular order?
12 A We weren’t told to return them, the Court did not order
13 us to return them.
14 Q But did the Court order you to do that at that time, do
15 you recall?
16 A I don’t know.
17 Q You took that order seriously enough so that you posted
18 it on your website, is that correct?
19 A Yes.
20 MR. MILSTEIN: Can you show the witness the order.
21 MR. LEHNER: Just so it’s in the record, I would
22 like to mark it.
23 THE COURT: Petitioner’s 9, order of Judge Cogan
24 filed December 29th.
25 Do you have a copy, ma’am?
180
1 THE WITNESS: Not yet.
2 MR. LEHNER: Just for housekeeping, I think we did
3 move the admission of Petitioner’s 8.
4 MR. MILSTEIN: I have no objection to the admission
5 of the order. I object to his characterization. He
6 characterized the order as saying it required the return of
7 the documents. The order requires no such thing.
8 THE COURT: That is true but for the sake of the
9 clarity of the record, I’ll introduce it as Petitioner’s 9
10 even though obviously it’s a part of the record.
11 (So marked in evidence Petitioner’s Exhibit 9.)
12 Q You have that order in front of you?
13 A Yes, I do.
14 Q Is that the order that you posted on your website?
15 A That may be. I have a blogger.
16 MR. LEHNER: Can we mark as the next exhibit
17 Petitioner’s 10.
18 THE COURT: Mark it in evidence Petitioner’s 10.
19 (So marked in evidence Petitioner’s Exhibit 10.)
20 THE COURT: Should you want a recess at any time,
21 just ask for it.
22 THE WITNESS: Thank you.
23 MR. LEHNER: May I approach the witness for a
24 minute?
25 THE COURT: Yes.
181
1 MR. LEHNER: Can I make sure they are in the right
2 order. They might have gotten — yes, that is fine.
3 (Pause.)
4 MR. MILSTEIN: Do you have a question?
5 Q Yes.
6 Have you had a chance to read that?
7 A I’m familiar with this, this is on our blogger.
8 MR. MILSTEIN: Just wait for the question.
9 MR. LEHNER: Your Honor, if I can hand her
10 Exhibit 8.
11 Q You said this is a blog that you maintained?
12 A Actually, it’s maintained by a scientist in the U.K.
13 Q This is a blog to which you post information, is that
14 correct?
15 A Yes.
16 Q And the particular information that is included on this
17 particular document that appeared on the website was posted by
18 you, is that correct?
19 A Not physically. It’s posted by the scientist.
20 Q It’s your content that you provided to somebody who
21 puts —
22 A Except for the first line, your esteemed author. I don’t
23 do that.
24 Q Other than that, these are your words that you wrote?
25 A Yes.
182
1 Q And had somebody put on the website, is that correct?
2 A Yes.
3 Q And the — I’ll turn your attention to the paragraph that
4 begins: “See the court injunction several of us received
5 below.”
6 Do you see that particular paragraph?
7 A Yes.
8 Q The — why don’t you just read that paragraph through to
9 the end, please.
10 A “See the court injunction several of us received below
11 but the internet is an uncontrolled information highway. You
12 never know where and when the court’s suppressed documents
13 might surface. The documents appear to be downloadable at —
14 and it provides two websites that I’m unfamiliar with. Do you
15 want me to read them?
16 Q No, that is all right. We’ll note there are two websites
17 here in the documents but these are website addresses that you
18 wrote put in this document that directs people to go to the
19 documents, is that correct?
20 A If they chose, yes.
21 Q And you were aware, however, that the order that you put
22 on the — and posted in this blog and had copied in there
23 suggested that those — suggested or not or ordered that the
24 temporary mandatory injunction requires the removal of any
25 such documents posted at the website?
183
1 A We did not have them at our website.
2 Q You read the order, is that correct?
3 A Yes.
4 Q And you understood that the order itself required that
5 the mandatory injunction required the removal of any such
6 documents posted at any website?
7 A Yes, but I have no control over what people put on their
8 websites.
9 Q But you did feel that you had not only the opportunity
10 but I guess you felt you had the obligation to direct people
11 the toward websites where you believed at least they could
12 find these documents which the Court had ordered to be removed
13 pursuant to the order of December 29th, is that correct?
14 A That’s correct.
15 Q Let me just ask one final question.
16 You mentioned that the group that you are associated
17 with the Alliance For Human Resource?
18 A Protection.
19 MR. MILSTEIN: Research.
20 A Research, Alliance For Human Research Protection.
21 Q That is a group?
22 A I am the president and founder.
23 Q Is that group affiliated with MindFreedom in any way?
24 A No.
25 Q Is it affiliated with NAPA in any way?
184
1 A No, we are strictly independent in every way, no funding
2 from industry.
3 MR. LEHNER: One more document to make sure that the
4 record is complete here.
5 THE COURT: Petitioner’s 11.
6 (Pause.)
7 Q Have you had an opportunity to review what has been
8 marked as Petitioner’s 11?
9 A Yes, I have.
10 MR. LEHNER: We move that into evidence, your Honor.
11 THE COURT: Yes.
12 (So marked in evidence Petitioner’s Exhibit 11.)
13 Q Why don’t you just tell us the dates on which this E-mail
14 was sent and received?
15 A It was sent on Sunday December 17th, the day that the
16 first article on the front page of the New York Times appeared
17 and I wrote a note to Jim: “Hope I get the copies.” I still
18 hadn’t had the copies. “I intend to call New York State
19 Attorney General Andrew Cuomo tomorrow to deliver, then will
20 send to other attorneys general. I think that is
21 ground-breaking. Lilly is finally haven’t a PT disaster. I’d
22 like to coordinate with you when you write up the summary of
23 threats, et cetera. Forward so that I can incorporate into
24 infomail and then P.S. your portrait is a third of the page.”
25 Q After you talked to Mr. Gottstein, you had asked him to
185
1 send you the DVDs because you had not been able to download
2 them from the link, is that correct?
3 A Yes.
4 Q And you signalled to him your intention then that it was
5 your desire to disseminate and spread this information as
6 broadly as you could at this point?
7 A In particular to the New York State Attorney General
8 after I read in the Times what was in the content of the
9 documents.
10 Q Before you read The Times, other than what you testified
11 to earlier about your suppositions of what might be in these
12 documents, did you have any other information that led you
13 specifically to believe — that led you to a specific belief
14 about what was in those documents?
15 A As I explained, there have been —
16 Q Let me strike that question and ask more particularly.
17 Did you and Mr. Gottstein when you talked to him
18 that day discuss the content of the documents?
19 A No.
20 MR. LEHNER: I have no further questions at this
21 time.
22 MR. HAYES: Nothing, judge.
23 MR. McKAY: Nothing.
24 CROSS-EXAMINATION
25 BY MR. MILSTEIN:
186
1 Q Ms. Sharav, can you tell the Court what the Alliance For
2 Human Research Protection is?
3 A We’re a group of professionals and lay people and our
4 mission is to protect the rights of human subjects in medical
5 research and to inform about concealed adverse drug events.
6 Q And if you can tell the Court something about your
7 background. Have you been asked the to testify or serve on
8 various government committees?
9 A Yes, I have. I’ve served, I have testified at various
10 government agencies including the FDA, the Institute of
11 Medicine, I presented at the National Academy of Science. I
12 was on the Children’s Committee of the — what was it called
13 then? The National Bioethics Advisory Committee and I’ve
14 presented before various bodies before the military, Columbia
15 University, Cornell University of Texas, primarily about both
16 unethical experiments and about the epidemic adverse effects
17 of drugs, particularly the psychotropic drugs but not
18 exclusively. Our organization focuses more generally but
19 there is a great deal in this area because vulnerable people
20 such as children and the elderly and disabled people are being
21 targeted to take drugs that are doing them more harm than
22 there is any evidence of benefit.
23 So that is why there is such a focus on this.
24 Q And in that experience that you’ve had, I take it you’ve
25 done a lot of research into the way drug companies market
187
1 their drugs?
2 A Yes, I have.
3 Q And the way they conduct research on their drugs?
4 A Yes, I have.
5 Q And I take it you consider it your life’s calling to
6 inform the public about unethical practices of pharmaceutical
7 companies like Eli Lilly?
8 A Absolutely.
9 Q Now, with respect to the conversations you had with Mr.
10 Gottstein, you did not receive the documents before the New
11 York Times published it’s front page article, is that right?
12 A That’s correct.
13 Q Mr. Gottstein didn’t tell you what the documents
14 contained?
15 A No, he did not.
16 Q Then you read the New York Times article?
17 A Yes, I did.
18 Q And after that, you received the documents by DVD from
19 Mr. Gottstein?
20 A Yes.
21 Q And did you have occasion to look at and read the
22 document?
23 A Yes, I have.
24 Q And what did the documents show with respect to the
25 practices of Eli Lilly?
188
1 MR. LEHNER: Objection, your Honor.
2 THE COURT: I’ll allow it.
3 A In my opinion, this is about the worst that I have seen.
4 It borders on indifference to human life. Eli Lilly knew that
5 Zyprexa causes hypoglycemia, diabetes, cardiovascular damage
6 and they set about both to market it unlawfully for off label
7 uses to primary care physicians and they even set about to
8 teach these physicians who were not used to prescribing these
9 kind of drugs to, they taught them to interpret adverse
10 effects from their drug Prozac and the other antidepressants
11 which induce mania and that is on the drug’s labels. They
12 taught them that if a patient presented with mania after
13 having been on antidepressants, that that was an indication
14 for prescribing Zyprexa for bipolar which is manic depression.
15 That is absolutely outrageous and that is one of the reasons
16 that I felt that this should involve the Attorney General.
17 Q What else did the documents say about the way Lilly
18 marketed its products?
19 A They marketed it, as I said, for off label uses which is
20 against the law. They told doctors — they essentially
21 concealed the vital information that they knew from the
22 prescribing doctors and covered it over, sugar coated it which
23 you can see the sales. The sales of a drug that was approved
24 for very limited indications, for schizophrenia and for
25 bipolar. Each one of these is about one to 2 percent of the
189
1 population. But the reason the drug became a four and a half
2 billion dollar seller in the United States is because they
3 encouraged the prescription for children, for the elderly, for
4 all sorts of reasons. The drug is being prescribed
5 irresponsibly because doctors have not been told the truth and
6 major study by the National Institute of Mental Health
7 validates this. It’s called the Catie study. It has been
8 published and they corroborate to such a degree the harm that
9 this drug is doing and the other so-called atypical
10 antipsychotics that leading psychiatrists who had been fans of
11 these drugs are now saying we were fooled, we didn’t realize.
12 It isn’t just weight gain. They are blowing up and it is
13 calling what is called metabolic syndrome, which is a cluster
14 of life-threatening conditions this drug is lethal and many
15 doctors now say it should be banned.
16 MR. LEHNER: Let me move to strike the testimony
17 again as being nonresponsive to the question that was being
18 asked.
19 THE COURT: It shows her state of mind.
20 Q In addition, are you familiar with a video recently
21 posted of a Lilly salesperson who talked about the way Lilly
22 markets the drugs?
23 A Yes.
24 Q Did that also mirror what these documents show?
25 A Absolutely. It appeared on U-Tube and we disseminated
190
1 that and in there the former Zyprexa salesman tells exactly
2 what they were taught and how they were taught to defuse
3 doctors’s concerns who saw their patients as he put it blow
4 up.
5 Q When you reviewed the documents, was there anything in
6 those documents that you viewed as trade secrets or
7 confidential information the way that phrase is usually
8 construed?
9 A Absolutely not.
10 MR. FAHEY: Objection.
11 A What it showed me was why they were willing to pay so
12 much money to keep them concealed.
13 MR. LEHNER: Same objection, no foundation for which
14 she could answer that question.
15 THE COURT: I’ll allow it. It shows state of mind.
16 Q After you received the notice from Mr. Gottstein, did you
17 disseminate the documents?
18 A No.
19 MR. MILSTEIN: That’s all I have, your Honor.
20 THE COURT: Anybody on the phone wish to examine?
21 MR. CHABASINSKI: No, your Honor.
22 THE COURT: Any redirect?
23 MR. LEHNER: No, your Honor, not at this time. The
24 only thing I ask is that the documents she brought with her be
25 returned to Mr. Woodin as they have been by the others in the
191
1 court.
2 THE COURT: Any objection?
3 MR. HAYES: No.
4 MR. MILSTEIN: We have an objection. That is what
5 this hearing is about, whether or not this Court will issue a
6 preliminary injunction ordering a person who did not act in
7 concert with nor did she aid or abet the distribution of these
8 documents by Dr. Egilman, whether this Court can order this
9 witness to return these documents.
10 MR. VON LOHMANN: Let me also just note for the
11 record, your Honor, none of the non-parties have been ordered
12 by this Court or any other Court to return these documents.
13 The January 4th order that your Honor signed also
14 asks simply that they not further disseminate the documents.
15 There is nothing in the January 4th order just as there was
16 nothing in the December 29 order suggesting that the Court is
17 ordering the return of those documents.
18 So what counsel here is asking for is not the
19 enforcement of a prior ruling, what counsel is asking here is
20 something entirely new.
21 MR. LEHNER: This Court asked Mr. Gottstein to
22 retrieve the documents and return them to Mr. Woodin, have
23 people return them directly to Mr. Woodin. That request was
24 based particularly with respect to the first order. She says
25 she has them. Other people felt compelled to comply with that
192
1 request.
2 MR. MILSTEIN: It’s a temporary restraining order
3 that was issued. If the court issues a preliminary injunction
4 order then Ms. Sharav is prepared to give the documents or the
5 DVDs to the special master.
6 If the Court dissolves the confidentiality order
7 with respect to the documents, as we have requested, or
8 decides not to issue a preliminary injunction, then she can
9 continue to hold on to these document and she can post them on
10 her website and distribute them to the public which needs to
11 see them to prevent further harm.
12 THE COURT: The order of December 18 from Judge
13 Cogan orders them returned, I believe.
14 MR. VON LOHMANN: I believe that order orders Mr.
15 Gottstein to request their return but especially considering
16 none of the parties are named in the order, I think it’s
17 certainly — I can’t speak for — none of these non-parties
18 even had seen this particular order at the time.
19 MR. MILSTEIN: And they did not request the New York
20 Times return the documents.
21 THE COURT: We don’t have the New York Times here.
22 We have your client.
23 MR. MILSTEIN: I understand that.
24 THE COURT: Unless you want to represent the New
25 York Times —
193
1 MR. MILSTEIN: The New York Times.
2 THE COURT: — and expand the orders to include it.
3 We can talk about the witness before us.
4 MR. MILSTEIN: The New York Times is noticeably
5 absent from the request of Eli Lilly to be ordered to return
6 these documents.
7 THE COURT: I understand.
8 Well, the order of December 18th requires Mr.
9 Gottstein to attempt to recover the documents.
10 MR. MILSTEIN: To request and she has refused Mr.
11 Gottstein. It doesn’t order her. It orders Mr. Gottstein to
12 ask her and she says no, I’m going to wait until the Court
13 orders me if the court can order me.
14 MR. McKAY: And Mr. Gottstein complied with respect
15 to that order.
16 THE COURT: He is here in court.
17 Paragraph 4 says: “Mr. Gottstein shall immediately
18 take steps to retrieve any documents subject to this order
19 regardless of their current location and return all such
20 documents to Special Master Woodin. ”
21 Come forward, sir.
22 Did you ask the witness to return the documents?
23 MR. GOTTSTEIN: Are you asking me if I did?
24 THE COURT: Yes.
25 MR. GOTTSTEIN: Would you return the documents?
194
1 THE WITNESS: I will return them if the Court orders
2 it.
3 THE COURT: You refuse to turn them over at his
4 request?
5 THE WITNESS: Yes.
6 THE COURT: I’m ordering you to turn them over to
7 your attorney to hold them in escrow.
8 MR. MILSTEIN: I’ll do that, your Honor.
9 THE COURT: Give the envelope to the attorney.
10 Are those all of the documents you have?
11 THE WITNESS: Yes.
12 THE COURT: You can seal it. Sign it. We’ll hold
13 them in escrow subject to — you’ll hold them in escrow
14 subject to the order of the Court.
15 MR. MILSTEIN: I’ll do that, your Honor.
16 THE COURT: Any reason why the witness should not
17 now be excused?
18 MR. HAYES: No, your Honor.
19 THE COURT: You are excused?
20 THE WITNESS: Thank you.
21 (Witness excused.)
22 MR. FAHEY: Your Honor, if we take a short break, we
23 can — if we can take a short break, we can have Mr. Meadow on
24 the phone who we believe will be a short witness.
25 THE COURT: It’s 10 to 4:00 we’ll break until 4:00

The weekends are always busy for me.  Today there was a meeting with SOAP.   I cannot attend all their meetings but today I was able to make it.   SOAP helped my  daughter move on from a place my daughter in her own words described as “prison”  – (documented  in my blog ‘Abuse at the Bethlem.’.   The group is made up of mainly former patients (survivors) who have had shocking care – some have written about their experiences and some have appeared on You Tube –  The group has a lot of members all over the country but meetings take place in London and today it was nice to meet two new members. We talked of experiences we have had with the services and current news and shared information.  I then went with a couple of members to further our conversation in a very nice coffee bar before leaving to go home.

I had spoken to Elizabeth earlier in the day.    With the long Bank Holiday weekend approaching I hope to have her to stay once again and then there is a family celebration shortly after this but need to see if I can get time off as Elizabeth will need someone there in the house with her.  The last visit went very well and was the first time  and I think benefitted Elizabeth.

I have posted on Twitter tonight in response of 10 minutes with the GP.   I pointed out that my daughter has been given a lifetime of drugging and also I had a lot more to say but my conversation was cut short as it was ‘not fair on the other patients.  Anyway at least I got to see the GP which is more than I can say for the Consultant Psychiatrist and I have asked to speak to her.   When you point out that the dosage is too high of Clozapine it is wrong that a consultant psychiatrist does not listen. and neither do they listen when a patients complains of serious side effects.    If Elizabeth is in bed around 6pm and has to rest in the afternoon it is obvious that the level of this drug is wrong and I have checked on this fact.  It should be minimal drugs not maximum and I did not like it one bit when the team gave me Lorazepam for Elizabeth and paracetamol on top.  Well I said to them that they should not prescribed these drugs on top as she was on quite enough.   I also pointed out how highly addictive Lorazepam is.  Elizabeth did not need any of these drugs during her stay with me .  The best cure is to lie down I did not have the need to give any further chemicals to my daughter – she is on quite enough in my opinion and the wrong dosage – too high.  Something is not right when Elizabeth sat in the garden with a thick coat and jumper on a hot sunny day and her hands were freezing cold.  I am now worried for her physical health which seems to be declining but the team do not seem concerned.  

TI hope there is better communication between the GP and psychiatrist.  I cannot believe how the team previously ignored the fact she was on contra indicated drugs.  I have made a point in discussing all of this with the new team as I do not want any more mistakes like this to happen with Elizabeth’s drugs and highly specialised advice needs to be sought if Elizabeth is going to be reduced off this level of Clozapine ie 350mg which is far too high.   If NICE have not got this down correctly then I will be phoning them  – I need to check on a few things in their guidelines tomorrow.    I am glad that Elizabeth reports that staff at this care home are nice to her particularly as I have been reading the most shocking reports about care homes and abuse to children.     One of the new members at the SOAP meeting revealed his experience of shocking abuse when he dared to request he took his medication in the evening as opposed to the teams demands and I cannot see anything unreasonable in this myself and he was not aggressive and certainly absolutely no signs of aggression was present in this member at all so what on earth is going on when 6-7 members of staff came in to restrain him and force him  to take the drugs there and then.  There are some professionals who really seem to like exerting their powers and I have come across much in the way of arrogance myself with staff smiling smugly during meetings.     When I look at the blog of MH Cop it makes me laugh when he refers to these wards as a place of safety –  it is not a place of safety and several of the patients including my daughter begged to go to prison instead.   I can quite understand why as you at least know when your sentence comes to an end –  under the MH a sentence can be like a life sentence.    Seeing as these patients are weak and vulnerable they are open to abuse but who is protecting them.  If you look on the Board of certain Advocates they have psychiatrists so nothing is done fairly.

MH Cop recently highlighted Nearest Relatives and the law however I can confirm that nothing is done in accordance with the law especially when a Tribunal is due to take place and the team wish to delay matters or when a team say they want someone to be on a Section 3 their behaviour amounts to harassment and anyone else would be cautioned for this.      it is easy to play on capacity and confidentiality.  After a while a patient becomes weakened on these awful drugs and loses strength to stand up to the staff –  then if they have a nearest relative who disagrees with what they are doing they try and get rid of that nearest relative instead of working with the family.   The excuse in my case was always unfounded in that they accused me of intending to take her off the drugs or encourage her to stop taking them.  It would seem that the  team care about more about the pushing of mind altering chemicals than the wellbeing of Elizabeth and her physical state of health.    How many times have I said I would not take her off the drugs –  I am not a doctor and she would need specialist help but if someone is suffering on these drugs where is that specialist help?  Coming off the drugs is risky but not impossible if done correctly and properly monitored and in the right environment.  No different that coming off illicit drugs yet no fuss is made about this. 

Lately I have passed on some very good advice I have received to the team  that 100mg is the therapeutic dose for Clozapine.- the easy solution is to just ignore matters.  Certainly the care home is not the right environment for any titration to be done that is for sure. 

Vast amounts of taxpayers money is being wasted on psychiatric drugs given to patients who are treatment resistant which means they cannot metabolize the drugs yet you read about patients with life threatening physical illnesses who are deprived life saving drugs because of cost.  When so much money is being wasted on psychiatric drugs that can be harmful if they do not work I just cannot see the sense in this at all.    

Anyway I have had a good day today and just a restful day at home to look forward to tomorrow.

At least now Elizabeth is not being deprived of seeing her family like before.

 

 

 

 

 

PITUITARY FUNCTIONI can identify with some of this article: the struggle to get the correct treatment – the damage that can be done to health if not getting the right treatment – the symptoms – Elizabeth has described some of these and over the weekend on a bright sunny day she was sitting in the garden with a thick coat and jumper and her hands freezing cold. I feel Elizabeth’s health is deteriorating and am trying to get the team to take notice of this. I have been looking up what tests should be done in terms of assessments and have had to go right to the top to get advice from Professors. I admire the strength of Christine – it should not be like this that you have to fight and struggle to get assessments etc. There should be proper assessments given for everyone before labelling a patient with a psychiatric condition when all along they could be physically ill. Before giving psychiatric drugs there should be tests to see if someone can metabolize them. There is no consideration for someone’s physical health whatsoever and this has a wider outcome – a strain to hospital resources – a waste of money to the taxpayer as patients become ill with serious long term health conditions. I would like to see change in this system as a mother who has had more than one person affected in my family and seen what damage these drugs have done to my elder daughter and to others.

HOPE SHARING THE FOLLOWING ADVICE BENEFITS MANY PEOPLE AS IT HAS DONE TO ELIZABETH AND MYSELF:
“It is an anecdotal case study and not a proper scientific paper. Hypothyroidism following brain injury is fully understood and detectable via observation on a number of endocrine pathways and pituitary dysfunction is one of the conditions I examined over a six year research programme on hormonal markers in cancer. You would be better off not frightening yourself by reading this stuff, it is of little value. Hyperthyroid states may cause symptoms similar to mania and physical signs of elevated thyroid hormones can be detected in the blood. Hyperthoroidism is associated with excessive activity, emotional instability, difficulty in interpersonal relationships due to irritability, excitability, impatience and liability to explosive rage. In predisposed subjects a schizophreniform picture may occur of short duration.

Classic schizophrenia is thought to be linked to dopamine which is why most anti-psychotic medications are dopamine receptor antagonists. The condition that biopsychs call ‘treatment refractive schizophrenia’ is probably not related to schizophrenia at all. They are using that somewhat all encompassing term because the refractive patient presents with signs similar to classic schizophrenia. This type of psychotic behaviour is common to many psychiatric states and occurs similarly in toxic states. A startling clue to the two conditions being unrelated is that Clozapine, given to refractive patients is a weak dopamine receptor antagonist meaning the symptoms cannot be liked to excessive dopamine in the brain. Clozapine inhibits 5-HT serotonin, muscarinic, histamine and most interestingly alpha-adreno-receptors. This links this condition irrefutable with endocrine dysfunction. It is because the drug companies have refused to accept this that thousands of patients have been forcibly drugged with medications directed at dopamine receptors when there was never anything wrong with that neurotransmission pathway. Millions of patients in the last 30 years have suffered the most severe extrapyramidal side effects because the anti-dopaminergic effect of these drugs has severely and irreversibly damaged their nervous systems and neurotransmission.

If patients have defective pituitary glands the entire endocrine system will be affected, parathyroid lesions also present in florid psychosis. So many of these medics do not even know this that it beggars belief. Any scientist studying the effect of iatrogenic injury to the nervous system will be familiar with this. I spent years looking at iatrogenic transmission of degenerative brain disorders via contaminated human growth hormone, a product of the pituitary gland and the effect that calcitonin has on the increase in cell motility in solid tumour metastasis. It took me a long time to get anywhere near an understanding of these processes and I know that many doctors have no idea of how this works.

Pass on this info to as many as you think may be able to use it, as ever. You never know, you may be able to get someone to listen to it one day.

Barry

I have another reason to suspect that the condition that psychiatrists refer to as treatment refractive schizophrenia is connected to endocrine dysfunction.  The drug Clozapine is the drug of choice in this condition, usually arrived at by a crude process of elimination after administering the range of drugs available for the treatment of psychoses.
 
Dopamine has been the main suspect in schizophrenia for years but to date this has not been categorically confirmed.  Nevertheless the main treatment for schizophrenia has been the drugs in the dopamine receptor antagonist class with some degree of success.
 
In treatment resistant forms of psychosis these drugs do not suppress the more florid symptoms  which indicate two possibilities.  The first is that the patient cannot metabolize these drugs due to deficiencies in cytochrome P450’s, the principal enzyme responsible for metabolizing anti-psychotic medication.  It is logical that a poor or non-metabolizer will not benefit from drugs requiring P4502D6, P450IA2, P4502C or P4503A. All the current drugs in the psycho-pharmacopeia  require these cytochromes for metabolism and apart from the possibility that the patient may be deficient, many other drugs interfere with the metabolism and pharmacokinetic properties. 
 
The drug Clozapine is unusual in that it is a weak antagonist at D2 receptors.  This casts some doubt on the dopamine theory as a cause of schizophrenia.  Clozapine inhibits α-adrenoreceptors, muscarinic, 5-HT and histamine receptors.  Risperidone is also a weak D2 antagonist and operates on 5-HT2 receptors.
 
The effect on 5-HT receptors is interesting in that elevation of cortisol after prolonged life stress may predispose a patient to mental illness by interfering with brain 5-HT function.  This offers an alternative cause of psychotic episodes less reliant on dopamine levels.  Endocrine disorders are associated with elevated cortisol.  Plasma cortisol is increased in about half of patients with depression but this is not specific to any particular depressive disorder and occurs also in mania and schizophrenia. 
 
Treatment refractive patients may not be suffering from classical dopamine related schizophrenia at all but their psychotic symptoms may be a result of an underlying endocrine dysfunction perhaps in the parathyroid or pituitary.    It is hardly surprising that they would not respond to the classic psychiatric medications based on dopamine receptor antagonists.
 

You may as usual distribute this to as many people as you think may be interested and I am happy that you cite me as author.  I am happy to join in any scientific debate on this subject with anyone interested.

 
Barry Turner

(Senior lecturer in media law, public administration and science and environmental journalism)

(NOTTINGHAM TRENT UNIVERSITY,  UNIVERSITY OF LINCOLN)

“I get up early, make breakfast according to my weekly plan (specifically devised diet). Usually I go out in the garden if the weather is fine then there are some activities. I take part in a “communal cook”. Twice a week there is a psychology group. We discuss things like diet, healthy eating and individual problems and how to solve them. Once a week I go with staff for a walk around the park opposite. There is a garden group but I have not yet taken part in this or the swimming group that go twice a week. The staff check up on me doing every day chores like washing/shopping and the shopping is done Tuesdays for which I have an allowance. I have not been out on my own at all – staff always accompany me and sometimes a member of staff will take me into town or help me do certain chores. I cannot go out on my own as I feel unsteady on my feet walking. I cannot sit down for longer than 5 minutes as I become fearful and feel restless. I do suffer from dizziness and am fearful of open spaces and suffer panic attacks. I think this could be because I was in hospital for so many years and did not go out much – again never on my own.

I get tired and have to go to bed early. I cannot stay up beyond 7.00 pm and sometimes after lunch I feel so tired I have to lie down. If I become stressed I feel a strain to my heart and get sharp pains.

It has been nice coming home over Easter. I have felt refreshed being at home with the family and have enjoyed staying with grandparents and my Mum. Things are getting better now that I am allowed more time to spend with my family whereas before I felt trapped and chlostrophobic.

I have listened to part of a broadcast – a friend of my Mum and her daughter and found this very interesting (Critical Mass Radio) The Lorraine Moss Show.

I am much happier at the home than before in hospital. The people are nice, both staff and residents.

Over the weekend I went to Woburn Abbey with my Mum. I would like to work with animals but I still enjoy cooking and do this every day. I also enjoy art. I was once on a floristry course. I have not long since moved to the care home and hope to move on with my life now.

Looking back to my experience at the hospitals I would have liked there to be more understanding from health professionals for patients in general as when you say you do not wish to do something they do not understand and try and force you. I have not experienced that kind of treatment where I am now.”

At first I thought this title which is recognised by the current team was ridiculous – I thought that “treatment resistant” = failure. I have since been reading up on this and have looked further as I do not accept this diagnosis and I am correct not to. There is no such thing as “treatment resistant” – it is all about the patient’s ability to metabolise the drug and I have been looking at Metabolic Monitoring for Patients on Anti-Psychotics Medications and also I would like the necessary tests done on Elizabeth regarding P450 cytochromes – as I have learned that many who suffer from psychiatric symptoms are most likely victims of injury not of disease and I believe that to be the case with Elizabeth and yet this has been dismissed by doctors and psychiatrists responsible for her care. When I have requested such tests the GPs do not know anything about this and I have not yet spoken with the new consultant psychiatrist. What on earth is going on when such important tests are not readily available to everyone? The fact is there is no biological marker for schizophrenia and it is therefore impossible to say it is “treatment resistant”. If my daughter is being given drugs when she is treatment resistant my fears are for her physical health and I now want further investigations and have had to look for more specialised care than what is currently available for the majority. The Government should be doing something about this as a matter of urgency.

I would just like to add that metabolite testing into routine medical practice not only would save money on drugs could ensure a patient has the correct treatment in line with their physical health instead of continuing with a drug treatment that could do more harm than good. Ultimately this would save money to the taxpayer as the wrong treatment could lead to serious long term health problems that could otherwise be addressed.

It is wrong that doctors continue to drug patients who have no clue as to how the drugs are affect the patient physiologically.

Patient’s lives are being put at risk whilst drug companies profit and this fact does not just apply to those with MH problems either. Something needs to be done about this situation.

%d bloggers like this: